The Concomitant Use of (1) Aminoglycoside Antibiotics (Gentamicin, Amikacin and Tobramycin) and (2) Kalydeco® (VX-770) in F508del/G542X Heterozygous Individuals with Cystic Fibrosis May Increase Readthrough of the G542X Premature Stop Codon and Potentiate the Functional G542X Containing CFTR Protein at the Apical Cell Membrane
The Concomitant Use of (1) Aminoglycoside Antibiotics (Gentamicin, Amikacin and Tobramycin) and (2) Kalydeco® (VX-770) in F508del/G542X Heterozygous Individuals with Cystic Fibrosis May Increase Readthrough of the G542X Premature Stop Codon and Potentiate the Functional G542X Containing CFTR Protein at the Apical Cell Membrane